Disease Biomarkers for Precision Medicine: Challenges and Future Opportunities
نویسندگان
چکیده
Center for Health Genomics and Informatics, University of Calgary Cumming School of Medicine, Calgary, AB T2N 4N1, Canada Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region Department of Health Technology and Informatics, Faculty of Health and Social Sciences, Hong Kong Polytechnic University, Hong Kong Special Administrative Region CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
منابع مشابه
A review on precision medicine and conducting pharmacogenetics tests of drugs
Precision medicine, the selection of treatment based on the genetic characteristics of patients, is one of the new paradigms of medical science. Using genetic characteristics and biomarkers, patients' response to different treatments is evaluated and finally, a specific one is selected for them. In other words, using genetic information or biomarkers, the safety, effectiveness and outcomes of t...
متن کاملPharmacogenomics and Global Precision Medicine in the Context of Adverse Drug Reactions: Top 10 Opportunities and Challenges for the Next Decade
In a move indicative of the enthusiastic support of precision medicine, the U.S. President Barack Obama announced the Precision Medicine Initiative in January 2015. The global precision medicine ecosystem is, thus, receiving generous support from the United States ($215 million), and numerous other governments have followed suit. In the context of precision medicine, drug treatment and predicti...
متن کاملFuture Challenges and Opportunities in Online Prescription Drug Promotion Research; Comment on “Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters”
Despite increased availability of online promotional tools for prescription drug marketers, evidence on online prescription drug promotion is far from settled or conclusive. We highlight ways in which online prescription drug promotion is similar to conventional broadcast and print advertising and ways in which it differs. We also highlight five key areas for future research: branded drug websi...
متن کاملOpportunities for the Cardiovascular Community in the Precision Medicine Initiative.
The Precision Medicine Initiative recently announced by President Barack Obama seeks to move the field of precision medicine more rapidly into clinical care. Precision medicine revolves around the concept of integrating individual-level data including genomics, biomarkers, lifestyle and other environmental factors, wearable device physiological data, and information from electronic health recor...
متن کاملDeveloping a molecular taxonomy for traumatic brain injury: a perspective to enable the development of diagnostics and therapeutics.
Traumatic brain injury (TBI) is a major cause of death and disability and one of the greatest unmet needs in medicine and public health [1,2]. It is considered “the most complex disease of our most complex organ”, strikingly heterogeneous in terms of mechanisms, pathology, severity and treatment, with widely varying outcomes [3]. To date, traditional, unidimensional and insensitive methods disc...
متن کامل